Understanding how traumatic brain injury softens brain tissue
Official title: Tissue Softening in Traumatic Brain Injury
Funded at University of Utah · NIH-11085947 · Data updated 2026-11-12
This study is looking at how a traumatic brain injury can make brain tissue softer and potentially lead to more injuries, using special imaging to better understand these changes and help improve ways to prevent and treat TBI.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | May 15, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $74,836 |
| NIH project number | 5R03NS137098-02 |
| Project ID | NIH-11085947 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced a traumatic brain injury.
✕Less likely to help
Patients who have not experienced a traumatic brain injury or are under 21 years old may not benefit from this research.
What this research studies
This research investigates the changes in brain tissue stiffness following traumatic brain injury (TBI). It aims to understand the mechanisms behind brain softening, which may increase the risk of further injury. The study utilizes advanced imaging techniques to analyze how deformation affects both the brain and its blood vessels. By examining these changes, the research seeks to provide insights that could improve prevention and treatment strategies for TBI.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for individuals suffering from traumatic brain injuries.
How similar studies have gone: While the specific mechanisms of brain softening post-TBI are not extensively studied, related research has shown promising results in understanding brain injuries and their effects.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Monson, Kenneth L — University of Utah
- Study coordinator: Monson, Kenneth L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.