Understanding how traumatic brain injury affects the immune system and healing
Mechanisms of Injury-induced Senescence and Immune-sequelae in Chronic TBI
['FUNDING_OTHER'] · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · NIH-10910113
This study is looking at how a traumatic brain injury affects your immune system and the stem cells in your bone marrow that help make immune cells, so we can better understand how these changes might impact your health and recovery over time.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10910113 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between traumatic brain injury (TBI) and the immune system's response. It focuses on how TBI alters the function of bone marrow stem cells, which are crucial for producing immune cells. By examining changes in blood cell types and immune responses after TBI, the research aims to uncover the mechanisms behind long-term effects on health and behavior. Patients may be monitored for changes in their immune system and overall recovery following TBI.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced a traumatic brain injury and are experiencing ongoing health issues related to their injury.
Not a fit: Patients who have not suffered a traumatic brain injury or those with acute, non-chronic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance recovery and improve quality of life for individuals with traumatic brain injuries.
How similar studies have performed: Previous research has shown promising results in understanding the immune response to brain injuries, suggesting that this approach could yield valuable insights.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RITZEL, RODNEY — UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
- Study coordinator: RITZEL, RODNEY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury