Understanding how transport proteins affect drug delivery during pregnancy
Diversity Supplement to Integrated Transporter Elucidation Center
This study is looking at how certain proteins in the placenta help move medications and nutrients to babies before they are born, with the goal of finding ways to improve care for mothers and their little ones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-11089683 on NIH RePORTER |
What this research studies
This research investigates the role of solute carriers (SLC) and ATP-binding cassette (ABC) transporters in the placenta, which are crucial for the transport of medications and nutrients to the developing fetus. By utilizing advanced techniques such as quantitative proteomics and genetic analysis, the study aims to identify factors that regulate these transporters. The research also employs computational modeling to predict how drugs and nutrients interact with these transport systems, ultimately aiming to improve therapeutic interventions for better perinatal healthcare.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals who are receiving medication or dietary supplements.
Not a fit: Patients who are not pregnant or those not taking any medications or supplements may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective drug therapies during pregnancy, enhancing fetal health outcomes.
How similar studies have performed: Previous research has shown promise in understanding transporter functions in other contexts, suggesting potential for success in this novel approach.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Aleksunes, Lauren M — Rutgers Biomedical and Health Sciences
- Study coordinator: Aleksunes, Lauren M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.