Understanding how transport proteins affect drug delivery during pregnancy
Official title: Integrated Transporter Elucidation Center
Funded at Rutgers Biomedical and Health Sciences · NIH-10929428 · Data updated 2026-11-12
This study is looking at how certain proteins help move medications and nutrients from a pregnant person to their baby, with the goal of finding ways to improve healthcare for both moms and their little ones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project start | September 14, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,055,800 |
| NIH project number | 5UC2HD113039-02 |
| Project ID | NIH-10929428 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant individuals who are taking medications or dietary supplements.
✕Less likely to help
Patients who are not pregnant or those not taking any medications or supplements may not benefit from this research.
What this research studies
This research investigates how medications and dietary supplements are transported across the placenta using specific proteins called solute carriers (SLC) and ATP-binding cassette (ABC) transporters. By studying these transporters, the research aims to understand their roles in delivering both drugs and essential nutrients to the developing fetus. The project utilizes advanced techniques, including proteomics and genetics, to identify factors that regulate these transporters, ultimately aiming to improve therapeutic interventions for better perinatal healthcare. The findings could help predict how drugs and nutrients affect fetal development.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective drug therapies during pregnancy, enhancing fetal health outcomes.
How similar studies have gone: Previous research has shown promise in understanding the roles of transport proteins in drug delivery, indicating that this approach could yield valuable insights.
Where this research is happening
-
Rutgers Biomedical and Health Sciences
Newark, United States Active
Researchers
- Principal investigator: Aleksunes, Lauren M — Rutgers Biomedical and Health Sciences
- Study coordinator: Aleksunes, Lauren M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.