Understanding how training can help recover vision after brain damage

Neuronal mechanisms underlying training-induced vision recovery

NIH-funded research Johns Hopkins University · NIH-11171670

This study is looking at how special training can help people who have lost their vision from strokes regain some sight by understanding how their brains adapt and change after the injury.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11171670 on NIH RePORTER

What this research studies

This research investigates how specific training can restore some vision in patients who have lost it due to damage in the primary visual cortex from strokes. By using an animal model, the study aims to explore the neuronal changes and circuit adaptations that occur in the brain after such injuries and subsequent training. The researchers will analyze how visual discrimination training affects the connections between different parts of the brain involved in vision processing. This approach could lead to new insights into therapies that enhance visual recovery in affected patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced occipital strokes resulting in cortically-induced blindness.

Not a fit: Patients with vision loss due to causes other than occipital strokes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved therapies that help restore vision in patients with cortically-induced blindness.

How similar studies have performed: Previous research has shown promise in using training to improve visual function in patients with similar conditions, suggesting that this approach may be effective.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.