Understanding how Toxoplasma gondii transports materials inside its cells
Intracellular cargo transport in Toxoplasma gondii
['FUNDING_OTHER'] · UNIVERSITY OF CONNECTICUT STORRS · NIH-10849886
This study is looking at how a parasite called Toxoplasma gondii moves important materials inside its cells, which could help us find new ways to treat diseases caused by similar parasites.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT STORRS (nih funded) |
| Locations | 1 site (STORRS-MANSFIELD, UNITED STATES) |
| Trial ID | NIH-10849886 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms of intracellular cargo transport in the parasite Toxoplasma gondii, which is part of a group of organisms that includes many significant human pathogens. The study aims to uncover how certain proteins, specifically actin and an unconventional myosin, facilitate the movement of materials within these cells. By exploring these processes, the research seeks to fill knowledge gaps in cellular biology and identify potential targets for new antiparasitic drugs. This could ultimately lead to advancements in treatment options for diseases caused by related parasites.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals affected by infections caused by Toxoplasma gondii or related parasites, particularly those who are immunocompromised.
Not a fit: Patients with non-parasitic infections or conditions unrelated to Toxoplasma gondii may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antiparasitic drugs that improve treatment for infections caused by Toxoplasma gondii and similar parasites.
How similar studies have performed: Other research has shown success in understanding cellular transport mechanisms in model organisms, but this specific approach in Toxoplasma gondii is relatively novel.
Where this research is happening
STORRS-MANSFIELD, UNITED STATES
- UNIVERSITY OF CONNECTICUT STORRS — STORRS-MANSFIELD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HEASLIP, AOIFE — UNIVERSITY OF CONNECTICUT STORRS
- Study coordinator: HEASLIP, AOIFE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.