Understanding how Toxoplasma gondii controls its mitochondria
Regulation of mitochondrial morphodynamics in Toxoplasma gondii
This study is looking at the special structure of a part of the Toxoplasma gondii parasite that helps it survive, with the hope of finding new ways to treat infections caused by it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project ID | NIH-11225243 on NIH RePORTER |
What this research studies
This research investigates the unique mitochondrial structure of the parasite Toxoplasma gondii, which is crucial for its survival and a potential drug target. The study focuses on the mechanisms that regulate the division and morphology of the mitochondrion, particularly how it changes shape during the parasite's life cycle. By identifying proteins involved in these processes, the research aims to uncover new insights that could lead to innovative treatments for infections caused by this parasite.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals infected with Toxoplasma gondii or those at risk of infection, particularly immunocompromised patients.
Not a fit: Patients who are not infected with Toxoplasma gondii or do not have a risk of exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new therapies targeting Toxoplasma gondii, potentially improving treatment options for patients with related infections.
How similar studies have performed: While the specific focus on mitochondrial morphodynamics in Toxoplasma gondii is novel, similar approaches in studying other parasites have shown promising results.
Where this research is happening
Amherst, United States
- State University of New York at Buffalo — Amherst, United States (Active)
Researchers
- Principal investigator: Arrizabalaga, Gustavo a — State University of New York at Buffalo
- Study coordinator: Arrizabalaga, Gustavo a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.