Understanding how tobacco use affects HIV and TB health outcomes in South Africa

Tobacco Use and Cessation, HIV, and TB in South Africa: Clinical and Economic Outcomes

NIH-funded research Massachusetts General Hospital · NIH-10889941

This study is looking at how smoking affects people with HIV and tuberculosis in South Africa and is trying to find the best ways to help them quit smoking while they receive care for these conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10889941 on NIH RePORTER

What this research studies

This research investigates the impact of tobacco use on individuals living with HIV and tuberculosis (TB) in South Africa. It aims to identify effective and cost-efficient strategies for integrating tobacco cessation into HIV and TB care. By developing a simulation model that incorporates behavioral, clinical, and economic data, the research seeks to inform clinical guidelines and improve health outcomes for affected populations. The study focuses on understanding the unique challenges faced in low- and middle-income countries, particularly in the context of overlapping epidemics.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals aged 21 and older who are living with HIV and/or TB and use tobacco.

Not a fit: Patients who do not use tobacco and are not affected by HIV or TB may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes for individuals with HIV and TB by effectively integrating tobacco cessation strategies into their care.

How similar studies have performed: Previous research has shown success in integrating tobacco control into care for chronic diseases, but this specific approach in the context of HIV and TB is relatively novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusCancersCardiovascular Diseases
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.