Understanding how to regenerate periodontal tissue
Cellular and molecular control of periodontal tissue regeneration
This study is looking at how certain stem cells in your gums can help heal and regenerate the tissue around your teeth, especially when there's inflammation, so that we can create better treatments to keep your gums healthy and prevent tooth loss.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11129036 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind the regeneration of periodontal tissue, which is crucial for maintaining healthy teeth. It focuses on identifying distinct populations of stem cells in the periodontal region and how these cells can be regulated to repair and regenerate damaged tissues. By exploring the effects of inflammation on these stem cells, the research aims to develop strategies for more effective periodontal treatments. Patients may benefit from advancements in therapies that restore periodontal health and prevent tooth loss.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults suffering from periodontal diseases or those at risk of tooth loss due to periodontal tissue damage.
Not a fit: Patients with healthy periodontal tissues or those without any periodontal disease may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for periodontal diseases, reducing tooth loss and enhancing oral health.
How similar studies have performed: Previous research has shown promise in using stem cell therapies for tissue regeneration, indicating potential success for this approach.
Where this research is happening
Boston, United States
- Harvard Medical School — Boston, United States (Active)
Researchers
- Principal investigator: Yang, Yingzi — Harvard Medical School
- Study coordinator: Yang, Yingzi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.