Understanding how to regenerate eyes using a frog model
Regulation of Eye Regrowth in Xenopus laevmis
This study is looking at how the clawed frog can regrow its eyes to help us understand how to encourage our own eye cells to heal better after injury, which could lead to new treatments for eye problems in people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nevada Las Vegas NIH-funded |
| Lab location | 1 site (Las Vegas, United States) |
| Project ID | NIH-10880668 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind eye regeneration using the clawed frog, Xenopus laevis, which has the ability to regrow functional eyes. The study focuses on identifying the signaling pathways and cell types necessary for effective tissue repair, particularly the role of bioelectrical signaling in promoting stem cell proliferation after injury. By exploring these processes, the research aims to uncover how to stimulate eye-specific stem cells for potential therapeutic applications in humans. The findings could provide insights into regenerative medicine and eye health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with eye injuries or degenerative eye conditions who are seeking innovative treatment options.
Not a fit: Patients with stable eye conditions that do not involve injury or degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for eye injuries or diseases that impair vision.
How similar studies have performed: Previous research has shown success in using bioelectrical signaling for limb regeneration, suggesting potential for similar breakthroughs in eye regeneration.
Where this research is happening
Las Vegas, United States
- University of Nevada Las Vegas — Las Vegas, United States (Active)
Researchers
- Principal investigator: Tseng, Kelly — University of Nevada Las Vegas
- Study coordinator: Tseng, Kelly
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.