Understanding how to promote healing in multiple sclerosis using a viral model
Defining mechanisms of disease and repair in a viral model of multiple sclerosis
This study is looking at how to help heal the nervous system in people with multiple sclerosis by using mice to learn more about certain signals that affect inflammation and the repair of damaged nerve cells, with the hope of finding better ways to improve recovery and lessen symptoms for MS patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11085957 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind multiple sclerosis (MS) and how to promote healing in the nervous system. By using a viral model in mice, the study aims to understand how certain signaling molecules, called chemokines, affect inflammation and the repair of damaged nerve cells. The researchers will explore how these signals influence the maturation of specific cells that are crucial for repairing myelin, the protective covering of nerves. The ultimate goal is to find effective ways to enhance nerve repair and reduce symptoms in MS patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with multiple sclerosis who are experiencing symptoms related to nerve damage.
Not a fit: Patients with other neurological conditions or those not diagnosed with multiple sclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that promote nerve repair and improve motor function in patients with multiple sclerosis.
How similar studies have performed: Previous research has shown promise in using similar approaches to understand and treat demyelinating diseases, indicating potential for success in this area.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Lane, Thomas E — University of California-Irvine
- Study coordinator: Lane, Thomas E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.