Understanding how to manage localized prostate cancer through active surveillance

Prostate cancer Active Surveillance Study (PASS) Cohort: Infrastructure Support for Cancer Research

NIH-funded research Fred Hutchinson Cancer Center · NIH-10691254

This study is looking at over 2,100 men with localized prostate cancer who are monitoring their condition instead of starting treatment right away, to find out more about how the cancer progresses and what factors can help predict outcomes, so that doctors can offer better, personalized care in the future.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionFred Hutchinson Cancer Center NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10691254 on NIH RePORTER

What this research studies

This research focuses on the Prostate cancer Active Surveillance Study (PASS) cohort, which includes over 2,100 men with localized prostate cancer who have chosen active surveillance as their management strategy. The study collects extensive clinical and epidemiological data, as well as biological samples, to better understand the progression of prostate cancer and the factors that influence patient outcomes. By analyzing this data, researchers aim to identify biomarkers that can predict cancer progression and improve personalized treatment approaches for patients. The infrastructure supported by this grant will ensure that valuable data and specimens are available for ongoing and future research.

Who could benefit from this research

Good fit: Ideal candidates for this research are men diagnosed with clinically localized prostate cancer who have opted for active surveillance.

Not a fit: Patients with advanced prostate cancer or those who are not eligible for active surveillance may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management strategies for men with localized prostate cancer, potentially reducing overtreatment and enhancing patient quality of life.

How similar studies have performed: Previous research has shown promise in using similar cohort studies to identify biomarkers and improve cancer management strategies.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.