Understanding how to maintain cognitive health in aging populations
Preserving Cognitive Resilience: A Biracial Parent-Offspring Study
This study is looking at what helps older adults stay sharp and healthy in their thinking, especially in biracial families, by checking brain scans and heart health in their middle-aged kids to see how their parents' brain health affects them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10897945 on NIH RePORTER |
What this research studies
This research investigates the factors that contribute to cognitive resilience in older adults, particularly focusing on biracial families. By examining neuroimaging biomarkers, cognitive tests, and cardiovascular risk factors in midlife, the study aims to identify protective factors that may help prevent cognitive decline. The research will enroll 750 offspring of participants from a previous study to explore the relationship between parental cognitive resilience and brain health in their children, while also considering differences across race and gender. The findings could lead to improved strategies for maintaining cognitive health as people age.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals aged in midlife whose parents were part of the CHAP biracial population study.
Not a fit: Patients who are not part of the biracial population or do not have a family history of cognitive resilience may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide insights into effective strategies for preventing cognitive decline in aging populations.
How similar studies have performed: Previous research has shown promising results in understanding cognitive resilience, particularly in minority populations, indicating that this approach has potential for success.
Where this research is happening
Chicago, United States
- Rush University Medical Center — Chicago, United States (Active)
Researchers
- Principal investigator: Rajan, Kumar B. — Rush University Medical Center
- Study coordinator: Rajan, Kumar B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.