Understanding how to keep mitochondria healthy
Homeostatic Mechanisms Regulating Mitochondrial Health
['FUNDING_OTHER'] · CALIFORNIA INSTITUTE OF TECHNOLOGY · NIH-10842342
This study is looking at how our cells keep their energy factories, called mitochondria, healthy and working well, which could help us understand more about diseases that affect energy production in the body.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CALIFORNIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (PASADENA, UNITED STATES) |
| Trial ID | NIH-10842342 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that maintain mitochondrial health, which is crucial for overall cellular function. It focuses on three key processes: the dynamics of mitochondrial fusion and fission, the selective degradation of damaged mitochondria through mitophagy, and the regulation of mitochondrial biogenesis. By using advanced techniques such as mouse genetics and cell biology, the research aims to fill important gaps in our understanding of how these processes work together to support cellular energy production and function. Patients may benefit from insights gained into mitochondrial health and its implications for various diseases.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with known mitochondrial dysfunction or diseases linked to mitochondrial health.
Not a fit: Patients with conditions unrelated to mitochondrial function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving mitochondrial function, potentially benefiting patients with mitochondrial disorders or related conditions.
How similar studies have performed: Other research has shown promising results in understanding mitochondrial dynamics and their role in health and disease, suggesting that this approach is building on established findings.
Where this research is happening
PASADENA, UNITED STATES
- CALIFORNIA INSTITUTE OF TECHNOLOGY — PASADENA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAN, DAVID C — CALIFORNIA INSTITUTE OF TECHNOLOGY
- Study coordinator: CHAN, DAVID C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.