Understanding how to involve individuals with Down syndrome in clinical trials.
DEtermining Capacity and Informing Down syndrome Assent Strategies (DECIDAS)
This study is looking at how people with Down syndrome can give their agreement to join clinical trials, making sure they are included in research in a fair way that respects their ability to make choices.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10696233 on NIH RePORTER |
What this research studies
This research focuses on individuals with Down syndrome (DS) and aims to develop a framework for obtaining assent for participation in clinical trials. It addresses the challenges faced by individuals with DS who may lack the capacity to make informed decisions about their involvement in research. By investigating the decision-making abilities of these individuals, the study seeks to create guidelines that ensure fair participation in clinical trials, ultimately improving the inclusivity of research for all individuals with DS.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with Down syndrome of all ages who may be considered for participation in clinical trials.
Not a fit: Patients without Down syndrome or those who are not involved in clinical trials may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more inclusive clinical trials for individuals with Down syndrome, enhancing the development of effective treatments.
How similar studies have performed: While there is limited research specifically addressing assent in individuals with Down syndrome, similar studies in other populations have shown success in developing frameworks for informed consent.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Combs, Daniel — University of Arizona
- Study coordinator: Combs, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.