NIH-funded research R21 grant

Understanding how to improve speech ability in children with Down Syndrome

Official title: Predictors of Speech Ability in Children with Down Syndrome

Funded at Vanderbilt University Medical Center · NIH-10316884 · Data updated 2026-11-12

This study is looking at what helps kids with Down Syndrome, ages 7 to 12, improve their speech skills, so they can communicate better, and it will use a special program to help them along the way.

More Down Syndrome research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startSeptember 1, 2021
Project endAugust 31, 2025
Funding year2021
Award (this year)$483,161
NIH project number1R21DC019280-01A1
Project IDNIH-10316884 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 7 to 12 years diagnosed with Down Syndrome.

Less likely to help

Patients outside the age range of 7 to 12 years or those without a diagnosis of Down Syndrome may not benefit from this research.

What this research studies

This research investigates the factors that influence speech ability in children with Down Syndrome, focusing on children aged 7 to 12 years. The study will measure speech articulation accuracy and intelligibility, along with cognitive and vocabulary skills, to identify predictors of speech development. A validated speech intervention will be employed to enhance speech intelligibility, allowing researchers to evaluate changes over time. By understanding these predictors, the research aims to inform future interventions that can help children communicate more effectively.

Why it matters

Potential benefit: If successful, this research could lead to improved speech communication skills for children with Down Syndrome, enhancing their educational and social experiences.

How similar studies have gone: Previous research has shown success with similar speech intervention approaches, indicating potential for meaningful advancements in this area.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Camarata, Stephen Mark — Vanderbilt University Medical Center
  • Study coordinator: Camarata, Stephen Mark

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.