Understanding how to improve recovery from post-surgical lymphedema

Novel Mechanisms in the Resolution of Post-Surgical Lymphedema

NIH-funded research Indiana University Indianapolis · NIH-11075832

This study is looking at how the body heals from swelling in the arms or legs after cancer surgery, and it aims to find new ways to help people recover better and feel more comfortable.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis NIH-funded
Lab location1 site (Indianapolis, United States)
Project IDNIH-11075832 on NIH RePORTER

What this research studies

This research investigates the mechanisms behind the resolution of post-surgical lymphedema, a condition that causes limb swelling due to lymphatic dysfunction often following cancer surgeries. The project aims to explore how spontaneous lymphovenous shunts and lymphangiogenesis contribute to the healing process. By studying both human patients and animal models, the research seeks to identify new treatment strategies that could enhance recovery and reduce complications associated with lymphedema. The principal investigator is a junior physician dedicated to advancing care for patients suffering from this chronic condition.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have developed lymphedema following cancer surgery, particularly those who have undergone lymph node excision.

Not a fit: Patients who have not undergone surgery or do not have lymphedema may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options and better recovery outcomes for patients with post-surgical lymphedema.

How similar studies have performed: Previous research has shown promise in understanding lymphatic function and recovery mechanisms, suggesting that this approach could yield valuable insights.

Where this research is happening

Indianapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.