Understanding how to improve care for infants with bronchopulmonary dysplasia as they transition from the NICU to home
Official title: Patient-Reported Outcomes to Understand Infant to Early Childhood Transition of Infants with Bronchopulmonary Dysplasia
Funded at Medical College of Wisconsin · NIH-11046004 · Data updated 2026-11-12
This study is all about finding better ways to support families of babies with bronchopulmonary dysplasia (BPD) as they transition from the hospital to home, by understanding their challenges and creating helpful tools to improve their health and care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | February 1, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $586,021 |
| NIH project number | 1R01HL171069-01A1 |
| Project ID | NIH-11046004 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are infants diagnosed with bronchopulmonary dysplasia who are transitioning from the NICU to home care.
✕Less likely to help
Patients who are not diagnosed with bronchopulmonary dysplasia or who are not transitioning from the NICU may not benefit from this research.
What this research studies
This research focuses on developing tools to measure the health outcomes of infants with bronchopulmonary dysplasia (BPD) as they move from the neonatal intensive care unit (NICU) to home. It aims to identify the challenges families face in accessing specialty care after discharge and to create strategies that can help reduce respiratory issues in these infants. By gathering insights directly from families, the research seeks to improve the overall care experience and health outcomes for these vulnerable children. The study will also address the lack of effective tools to assess respiratory symptoms specific to this population.
Why it matters
Potential benefit: If successful, this research could lead to better health management and improved quality of life for infants with bronchopulmonary dysplasia and their families.
How similar studies have gone: While there have been studies on respiratory outcomes in pediatric asthma, this research is novel in its focus on the specific needs of infants with bronchopulmonary dysplasia during their transition home.
Where this research is happening
-
Medical College of Wisconsin
Milwaukee, United States Active
Researchers
- Principal investigator: Lagatta, Joanne M — Medical College of Wisconsin
- Study coordinator: Lagatta, Joanne M
Related research
Other NIH-funded projects on the same topics.
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Role of uneven lung growth in chronic lung disease from birth to adulthood
This grant explores how mismatched growth of airways, airspaces, and blood vessels during early life might lead to lasting lung problems in bronchopulmonary dysplasia and how that affects people over time.
-
Regulatory T Cells and Lung Disease-Related High Blood Pressure in Adults
This project studies how a type of immune cell called regulatory T cells may influence inflammation and blood vessel changes in lung disease, with potential relevance to adults who have vascular issues in their lungs.
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Understanding how breathing effort in premature babies with lung disease comes from different lung problems
A research project aims to create a patient-specific tool to measure how different features of bronchopulmonary dysplasia contribute to the struggle to breathe in premature infants.
-
Role of LKB1 in reduced lung blood vessel growth in BPD
Aims to understand how a cellular regulator (LKB1) affects blood vessel formation in the lungs of preterm infants at risk for bronchopulmonary dysplasia.
-
A new approach to prevent bronchopulmonary dysplasia in preterm infants
A new treatment strategy aimed at improving lung development in premature babies at risk for bronchopulmonary dysplasia.
-
L-Citrulline for BPD-related Pulmonary Hypertension in Preterm Babies
A first-in-human study will test safe and effective doses of L-citrulline given by mouth to stability-preterm infants at risk for lung blood pressure problems.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.