Understanding how to improve bone growth and healing
Regulation of Skeletal Growth and Regeneration
This study is looking at how bones grow and heal in kids, especially focusing on the growth plates that help bones develop, to find ways to improve healing for those with injuries or bone problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11045204 on NIH RePORTER |
What this research studies
This research focuses on the mechanisms that regulate skeletal growth and regeneration, particularly in children. It investigates how growth plates, which are crucial for bone development, function and how they can be affected by injuries, genetic disorders, or medications. By studying the cellular and molecular processes involved, the research aims to identify potential therapeutic targets to enhance bone healing and growth in affected individuals. The research will involve both laboratory studies and potential clinical applications to improve outcomes for patients with skeletal issues.
Who could benefit from this research
Good fit: Ideal candidates for this research include children with growth plate injuries, genetic conditions affecting bone growth, or those experiencing side effects from medications that impact skeletal development.
Not a fit: Patients with fully developed skeletons or those without skeletal growth issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve bone growth and healing in children with skeletal disorders or injuries.
How similar studies have performed: Previous research has shown promising results in understanding skeletal growth mechanisms, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Pacifici, Maurizio — Children's Hosp of Philadelphia
- Study coordinator: Pacifici, Maurizio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.