Understanding how to improve awareness of low blood sugar in people with type 1 diabetes
Characterizing the evolution of impaired hypoglycemia awareness in people with type 1 diabetes and the impact of automated insulin delivery and exercise on restoring hypoglycemia awareness
['FUNDING_U01'] · UNIVERSITY OF MELBOURNE · NIH-11077195
This study is looking at how using automated insulin delivery systems and doing high-intensity interval exercise can help adults with type 1 diabetes regain their ability to sense when their blood sugar is low, which is really important for staying healthy.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MELBOURNE (nih funded) |
| Locations | 1 site (MELBOURNE, AUSTRALIA) |
| Trial ID | NIH-11077195 on ClinicalTrials.gov |
What this research studies
This research investigates the problem of impaired hypoglycemia awareness (IAH) in adults with type 1 diabetes, which can lead to severe health risks. The study will explore how automated insulin delivery systems and high-intensity interval exercise can help restore awareness of low blood sugar levels. By conducting a randomized-controlled trial, researchers aim to understand the evolution of IAH and the effectiveness of these interventions over time. Participants will be monitored to assess changes in their hypoglycemia awareness and overall health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with type 1 diabetes who experience impaired hypoglycemia awareness.
Not a fit: Patients who do not have type 1 diabetes or those who do not experience issues with hypoglycemia awareness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the safety and quality of life for individuals with type 1 diabetes by restoring their awareness of low blood sugar.
How similar studies have performed: While there have been limited successes with similar interventions, this research aims to provide new insights and potentially more effective strategies for managing impaired hypoglycemia awareness.
Where this research is happening
MELBOURNE, AUSTRALIA
- UNIVERSITY OF MELBOURNE — MELBOURNE, AUSTRALIA (ACTIVE)
Researchers
- Principal investigator: O'NEAL, DAVID NORMAN — UNIVERSITY OF MELBOURNE
- Study coordinator: O'NEAL, DAVID NORMAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.