Understanding how to improve adherence to cognitive training for better brain health

vmPFC's role in adherence to cognitive training

NIH-funded research Stanford University · NIH-10825578

This study is looking at ways to help people stick with brain training exercises that may slow down memory loss and Alzheimer's, using special breathing techniques to make the training more engaging, and it’s open to both individuals with mild cognitive issues and those without.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10825578 on NIH RePORTER

What this research studies

This research investigates how to enhance adherence to cognitive training programs aimed at slowing cognitive aging and Alzheimer's disease. It focuses on the role of the ventromedial prefrontal cortex (vmPFC) and employs resonance frequency breathing techniques to potentially improve engagement with cognitive training. Participants will be involved in an 8-week home-based training program, with assessments to measure their adherence and cognitive performance. The study compares different groups, including those with mild cognitive impairment and healthy controls, to understand the mechanisms behind effective cognitive training.

Who could benefit from this research

Good fit: Ideal candidates include individuals with mild cognitive impairment or healthy older adults interested in cognitive training.

Not a fit: Patients with severe cognitive impairment or those not interested in cognitive training may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for maintaining cognitive health and preventing decline in aging populations.

How similar studies have performed: Previous research has shown promise in using cognitive training and adherence strategies, making this approach both relevant and potentially impactful.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.