Understanding how to better treat chronic coughing in patients with cough hypersensitivity syndrome.
Official title: Identifying Predictors of Treatment Response to Pharmacologic and Nonpharmacologic Interventions in Cough Hypersensitivity Syndrome
Funded at Univ of North Carolina Chapel Hill · NIH-10985323 · Data updated 2026-11-12
This study is looking at ways to help people with cough hypersensitivity syndrome (CHS) by figuring out which treatments, like medications or therapy, work best for different individuals, so you can get the right help without the guesswork.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $142,804 |
| NIH project number | 1K23HL169934-01A1 |
| Project ID | NIH-10985323 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who experience chronic coughing associated with cough hypersensitivity syndrome.
✕Less likely to help
Patients with chronic cough not related to cough hypersensitivity syndrome may not benefit from this research.
What this research studies
This research investigates cough hypersensitivity syndrome (CHS), a condition marked by chronic coughing that can lead to serious health issues. The study aims to identify predictors of treatment response to both pharmacologic options, like medications and nerve blocks, and nonpharmacologic approaches, such as cognitive behavioral therapy through speech therapy. By analyzing cough symptoms, the research seeks to categorize patients into subgroups that will help determine the most effective treatment for each individual, moving away from a trial-and-error approach. This could lead to more personalized and effective treatment strategies for those suffering from CHS.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored treatments for patients suffering from chronic coughing due to cough hypersensitivity syndrome.
How similar studies have gone: Preliminary work has shown promise in identifying cough symptomology as a predictor for treatment response, indicating potential success in this area of research.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Novaleski, Carolyn K. — Univ of North Carolina Chapel Hill
- Study coordinator: Novaleski, Carolyn K.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.