Understanding how tissues repair themselves after injury
Official title: Mechanisms of Tissue Repair
Funded at Vanderbilt University · NIH-11011718 · Data updated 2026-11-12
This study is looking at how our bodies heal wounds and repair tissues, using fruit flies to learn more about how cells move and grow to fix damage, with the hope of finding better treatments for wounds that don’t heal well.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project start | May 1, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $311,770 |
| NIH project number | 1R35GM156631-01 |
| Project ID | NIH-11011718 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults suffering from non-healing wounds or injuries, particularly those related to chronic conditions.
✕Less likely to help
Patients with acute injuries that heal normally or those without any tissue repair issues may not benefit from this research.
What this research studies
This research investigates the mechanisms behind tissue repair and wound healing in humans, focusing on how cells migrate and proliferate to restore function after damage. Using a model organism, Drosophila, the team studies the cellular processes involved in repairing epithelial tissues and the basement membrane, which are crucial for organ function. The research aims to uncover the regulatory mechanisms that control tissue repair, which could lead to new therapies for non-healing wounds and injuries. Collaborations with physical scientists enhance the understanding of these processes through advanced imaging techniques.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for patients with chronic wounds and injuries that do not heal properly.
How similar studies have gone: Previous research has shown promise in understanding tissue repair mechanisms, but this approach using Drosophila as a model is relatively novel.
Where this research is happening
-
Vanderbilt University
Nashville, United States Active
Researchers
- Principal investigator: Page-Mccaw, Andrea — Vanderbilt University
- Study coordinator: Page-Mccaw, Andrea
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.