Understanding how tiny particles affect allergic lung disease
Mechanisms of Nanoparticle Modulation of Allergic Lung Disease
This project explores how tiny engineered particles might make allergic lung conditions, like asthma, worse for people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-11118845 on NIH RePORTER |
What this research studies
We know that tiny engineered particles, called multi-walled carbon nanotubes, are used in many products and might be harmful to our lungs. This project aims to understand how these particles could make allergic lung conditions, like asthma, worse. Researchers believe these particles might attach to common allergens, making them more potent and triggering harmful responses in lung cells. By understanding these processes, we hope to find new ways to protect our lungs from these environmental triggers.
Who could benefit from this research
Good fit: Patients with allergic asthma who are exposed to environmental nanoparticles might benefit from this future knowledge.
Not a fit: Patients seeking immediate new treatments or direct participation in a clinical trial would not find direct benefit from this foundational research.
Why it matters
Potential benefit: This could lead to new ways to prevent or treat allergic lung diseases worsened by environmental particles.
How similar studies have performed: This research builds on existing evidence from animal models and preliminary findings, exploring a specific mechanism that is not fully understood.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Bonner, James Christopher — North Carolina State University Raleigh
- Study coordinator: Bonner, James Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.