Understanding how tiny embryos make proteins

Single cell quantification of translation control in early mouse development

['FUNDING_OTHER'] · UNIVERSITY OF TEXAS AT AUSTIN · NIH-11137613

This research looks at how very early embryos create proteins, which is essential for healthy development.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS AT AUSTIN (nih funded)
Locations1 site (AUSTIN, UNITED STATES)
Trial IDNIH-11137613 on ClinicalTrials.gov

What this research studies

In the earliest stages of life, before an embryo can make its own genetic instructions, it relies on existing instructions to build proteins. This process, called translation, is crucial for an embryo to develop properly, and if it's blocked, development stops. Researchers are using new technology to precisely measure how proteins are made in single early embryos. This will help us understand the exact steps and mechanisms involved in healthy early development.

Who could benefit from this research

Good fit: This foundational research is not directly recruiting patients but could eventually benefit future parents and children affected by congenital abnormalities or early developmental issues.

Not a fit: Patients seeking immediate treatment or direct clinical intervention for existing conditions would not directly benefit from this basic science research.

Why it matters

Potential benefit: This work could help us understand the fundamental causes of birth defects and developmental problems by revealing how early embryos develop normally.

How similar studies have performed: This approach uses a new technology to measure protein production in single embryos, making it a novel and previously unexplored area.

Where this research is happening

AUSTIN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.