Understanding how tics change over time in Tourette Syndrome
Official title: Computational Modeling of Tic Change Trajectories in Tourette Syndrome
Funded at University of Minnesota · NIH-10865360 · Data updated 2026-11-12
This study is looking at how tic symptoms change over time in kids and teens with Tourette Syndrome, using cool tools like apps and wearables to gather information, so we can find better ways to help manage their tics and improve their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $201,488 |
| NIH project number | 1K23MH136409-01 |
| Project ID | NIH-10865360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and adolescents diagnosed with Tourette Syndrome who are experiencing tic symptoms.
✕Less likely to help
Patients who do not have Tourette Syndrome or those who are not within the pediatric age range may not benefit from this research.
What this research studies
This research focuses on tracking and analyzing the changes in tic symptoms over time in children and adolescents with Tourette Syndrome. Using advanced data collection methods such as electronic assessments and wearable devices, the research aims to gather detailed information about tic behaviors and their responses to behavioral interventions. The principal investigator will lead clinical trials and manage large datasets to better understand how these symptoms evolve and how interventions can be tailored to improve outcomes for patients. The goal is to enhance the understanding of tic disorders and develop effective treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment approaches for managing tic disorders in youth.
How similar studies have gone: Previous research has shown promise in using multi-method approaches to understand tic disorders, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Wellen, Brianna C — University of Minnesota
- Study coordinator: Wellen, Brianna C
Related research
Other NIH-funded projects on the same topics.
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Precision brain mapping of tics in children with Tourette syndrome
A new study uses advanced MRI to map brain activity in individual kids with Tourette syndrome to understand why tics differ from child to child.
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Digital tic-detection partner to support Tourette syndrome therapy
A computer vision system will help detect tics in children and youths with Tourette syndrome to support behavioral therapy at home and in real life.
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Quantifying Tourette tics with video and computer tools
This project aims to develop and test video-based, automated ways to measure tic severity in people with Tourette Syndrome.
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Brain-feedback training to help teens with Tourette control tics
This project teaches teenagers with Tourette syndrome to use real-time MRI brain-feedback to change activity in a motor brain area with the goal of reducing tics.
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International collaboration mapping genes and brain scans in Tourette syndrome
This project brings together MRI brain scans and genetic data from people with Tourette syndrome and related conditions to spot biological patterns linked to tics and co-occurring symptoms.
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How Tourette syndrome develops in the brain
Researchers are using donated brain tissue and patient-derived stem cells to learn why people with Tourette syndrome have fewer specific brain cells in the basal ganglia.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.