Understanding how ticks develop and transmit diseases like Lyme disease and anaplasmosis
Ixodes scapularis Immuno-Developmental and Metabolic Signaling Pathways and Interference with Ticks and Tick-borne Pathogens
['FUNDING_P01'] · UNIV OF MARYLAND, COLLEGE PARK · NIH-11112741
This study is looking at how certain signals in ticks, especially the ones that carry Lyme disease, affect their growth and feeding habits, with the hope of finding new ways to control ticks and help prevent the spread of diseases they carry.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MARYLAND, COLLEGE PARK (nih funded) |
| Locations | 1 site (COLLEGE PARK, UNITED STATES) |
| Trial ID | NIH-11112741 on ClinicalTrials.gov |
What this research studies
This research investigates the molecular mechanisms that govern the development and metabolism of ticks, specifically the Ixodes scapularis species, which are known carriers of Lyme disease and anaplasmosis. By exploring newly recognized signaling pathways in ticks, the research aims to understand how these pathways influence tick behavior and their ability to transmit pathogens. The approach includes manipulating tick signaling through techniques like RNA interference to disrupt their feeding and pathogen transmission processes. This could lead to innovative strategies for controlling tick populations and reducing disease transmission.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in areas where Lyme disease and anaplasmosis are prevalent, particularly those who have had previous tick exposure.
Not a fit: Patients who do not live in tick-endemic regions or those who have not been exposed to ticks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective vaccines or treatments that reduce the incidence of tick-borne diseases in humans.
How similar studies have performed: Previous research has shown promise in understanding tick biology and developing anti-tick vaccines, indicating that this approach has potential for success.
Where this research is happening
COLLEGE PARK, UNITED STATES
- UNIV OF MARYLAND, COLLEGE PARK — COLLEGE PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PAL, UTPAL — UNIV OF MARYLAND, COLLEGE PARK
- Study coordinator: PAL, UTPAL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.