Understanding how thumb muscle mechanics affect pain and instability in osteoarthritis
Carpometacarpal Osteoarthritis: Understanding the Intersection of Muscle Mechanics, Joint Instability, and Pain
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-11078306
This study is looking at how the muscles in your thumb work and how that relates to the pain and problems people with thumb arthritis experience, with the hope of finding better ways to help those affected.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-11078306 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between thumb muscle mechanics and the symptoms of carpometacarpal osteoarthritis (CMC OA), which can significantly impair hand function. By studying individuals with varying degrees of CMC OA and healthy controls, the research aims to evaluate how changes in muscle structure and activity influence pain and joint instability. Advanced techniques such as ultrasound imaging and musculoskeletal simulations will be used to gather data on muscle characteristics and their impact on function. The goal is to identify factors that could lead to improved treatments for those suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with carpometacarpal osteoarthritis, regardless of the severity of their symptoms.
Not a fit: Patients without carpometacarpal osteoarthritis or those with other unrelated hand conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options that alleviate pain and restore hand function for patients with carpometacarpal osteoarthritis.
How similar studies have performed: Previous research has shown promising results in understanding the biomechanics of osteoarthritis, suggesting that this approach could yield valuable insights.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NICHOLS, JENNIFER A. — UNIVERSITY OF FLORIDA
- Study coordinator: NICHOLS, JENNIFER A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.