NIH-funded research R01 grant

Understanding how the visual cortex processes complex visual information.

Official title: Development and plasticity of stimulus processing in the visual cortex

Funded at State University of New York at Buffalo · NIH-10929299 · Data updated 2026-11-12

This study looks at how the brain learns to see and understand complex images, especially when it hasn't had enough visual experiences during important growth stages, and it could help find new ways to improve vision problems like lazy eye.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startSeptember 30, 2023
Project endJune 30, 2027
Funding year2024
Award (this year)$512,720
NIH project number5R01EY034644-02
Project IDNIH-10929299 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include adults with amblyopia or other visual processing disorders.

Less likely to help

Patients with fully developed visual systems and no history of visual deprivation may not receive any benefit from this research.

What this research studies

This research investigates how the visual cortex develops and adapts to process complex visual stimuli, particularly in the context of visual deprivation during critical developmental periods. By studying the neural responses in the visual cortex of mice, the researchers aim to identify when and how the ability to process complex visual features matures. The study employs advanced techniques, including 2-photon imaging, to observe neural activity and assess the impact of visual experiences on sensory processing. The findings could provide insights into potential interventions for visual impairments like amblyopia.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for treating visual disorders and improving visual function in affected individuals.

How similar studies have gone: Previous research has shown success in understanding visual processing in simpler contexts, but this approach to complex visual stimuli is relatively novel.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Kuhlman, Sandra J — State University of New York at Buffalo
  • Study coordinator: Kuhlman, Sandra J

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.