Understanding how the uterus develops and its role in pregnancy
Official title: Molecular and Cellular Regulation of Uterine Morphogenesis
Funded at University of Tx Md Anderson Can Ctr · NIH-11031294 · Data updated 2026-11-12
This study is looking at how the uterus forms in embryos to understand why some women have uterine problems that can cause infertility or miscarriage, and it hopes to find ways to improve care for these issues.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | February 3, 2024 |
| Project end | February 2, 2027 |
| Funding year | 2025 |
| Award (this year) | $37,524 |
| NIH project number | 5F31HD113306-02 |
| Project ID | NIH-11031294 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women with a history of miscarriage or infertility, particularly those diagnosed with congenital uterine anomalies.
✕Less likely to help
Patients without any history of reproductive issues or congenital uterine anomalies may not receive direct benefits from this research.
What this research studies
This research investigates the molecular and cellular processes involved in the development of the uterus, particularly focusing on the fusion of the Müllerian ducts during embryonic development. By studying the genetic and molecular mechanisms that regulate this process, the research aims to uncover why some women experience congenital uterine anomalies that can lead to infertility or miscarriage. The approach includes using animal models to observe the effects of specific genes on uterine formation. This knowledge could help in developing better management strategies for reproductive diseases in women.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for women facing infertility or pregnancy complications due to uterine anomalies.
How similar studies have gone: Previous research has shown success in understanding uterine development and its implications for reproductive health, making this study a continuation of established scientific inquiry.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Machado, Diana — University of Tx Md Anderson Can Ctr
- Study coordinator: Machado, Diana
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.