Understanding how the TBX3 gene affects breast cancer
Mechanism of Action of the TBX3 Gene in Breast Cancer
This study is looking at how a gene called TBX3 affects breast cancer by checking out a key signaling pathway that helps cells grow and stay healthy, with the goal of finding new ways to treat breast cancer for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10908281 on NIH RePORTER |
What this research studies
This research investigates the role of the TBX3 gene in breast cancer by exploring the WNT signaling pathway, which is crucial for cell development and tissue maintenance. The study aims to uncover how this signaling pathway is altered in cancer, particularly focusing on the mechanisms that lead to cancer progression and metastasis. By examining the molecular events involved in the formation and degradation of the WNT signalosome, researchers hope to identify new therapeutic targets that could lead to more effective treatments for breast cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with breast cancer who are interested in understanding the genetic factors influencing their condition.
Not a fit: Patients with non-breast cancer types or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new therapies that more effectively target breast cancer.
How similar studies have performed: Previous research has shown promising results in targeting WNT signaling pathways in cancer treatment, indicating that this approach has potential for success.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Agajanian, Megan — Stanford University
- Study coordinator: Agajanian, Megan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.