Understanding how the spinal cord generates movement rhythms
Mechanisms of locomotor rhythm generation in rodent spinal cord
This study is exploring how the spinal cord helps us move rhythmically, even after injuries like a stroke, and aims to find ways to activate these movement pathways to help people with movement difficulties get back on their feet.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10929517 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind how the spinal cord produces rhythmic movements, which are essential for locomotion. It focuses on the spinal circuits that remain functional even after injuries like spinal cord damage or stroke. By using various stimulation methods, the research aims to activate these circuits to restore movement. The study seeks to uncover the specific properties and interactions of neurons that contribute to coordinated movement, which could lead to new therapies for individuals with movement impairments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with spinal cord injuries, strokes, or movement disorders such as ataxia.
Not a fit: Patients with conditions unrelated to spinal cord function or those who do not have movement impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help restore movement in patients with spinal cord injuries or strokes.
How similar studies have performed: Other research has shown promise in using spinal stimulation techniques to restore movement, indicating that this approach has potential for success.
Where this research is happening
Philadelphia, United States
- Drexel University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Dougherty, Kimberly J — Drexel University
- Study coordinator: Dougherty, Kimberly J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.