Understanding how the retina processes visual information and what causes vision loss.
BLR&D Research Career Scientist Award
['FUNDING_OTHER'] · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · NIH-11106008
This study is looking at how the eye processes images and what early changes happen in the retina that can lead to vision loss from conditions like glaucoma and macular degeneration, especially in older adults, with the hope of finding new ways to help prevent or treat these eye problems.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VA GREATER LOS ANGELES HEALTHCARE SYSTEM (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11106008 on ClinicalTrials.gov |
What this research studies
This research program aims to explore the mechanisms that allow the retina to process visual images and to identify early cellular changes that lead to vision loss due to diseases affecting the retina and optic nerve. It involves studying the functional organization of the retina, focusing on specific types of retinal cells and their connections, as well as the signaling molecules involved in visual processing. By understanding these processes, the research seeks to uncover the underlying causes of conditions like glaucoma and macular degeneration, which are particularly relevant to the aging population. The findings could pave the way for new therapies to prevent or treat these eye diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing vision loss or at risk for retinal diseases such as glaucoma, macular degeneration, or diabetic retinopathy.
Not a fit: Patients with non-retinal related vision issues or those without any risk factors for retinal diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent or slow down vision loss in patients with retinal diseases.
How similar studies have performed: Previous research has shown promise in understanding retinal mechanisms and developing therapies for retinal diseases, indicating that this approach has potential for success.
Where this research is happening
LOS ANGELES, UNITED STATES
- VA GREATER LOS ANGELES HEALTHCARE SYSTEM — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRECHA, NICHOLAS C. — VA GREATER LOS ANGELES HEALTHCARE SYSTEM
- Study coordinator: BRECHA, NICHOLAS C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.