Understanding how the retina develops during embryonic growth
Determining the cell fate programs of mammalian retina development
['FUNDING_FELLOWSHIP'] · CALIFORNIA INSTITUTE OF TECHNOLOGY · NIH-10917118
This study is looking at how the cells in the eye's retina grow and work together during development, which could help us learn more about eye conditions like blindness.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CALIFORNIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (PASADENA, UNITED STATES) |
| Trial ID | NIH-10917118 on ClinicalTrials.gov |
What this research studies
This research investigates the processes involved in the development of the retina, focusing on how different cell types form and interact during embryonic growth. By using advanced molecular recording technologies and genome editing techniques, the study aims to create a detailed lineage history of retinal cells, capturing their transcriptional states and spatial positions. This approach will help researchers understand the regulatory mechanisms that dictate cell fate and organization within the retina, potentially leading to insights into conditions like blindness.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 21 years old who may be affected by retinal disorders or are interested in the biological mechanisms of eye development.
Not a fit: Patients with fully developed retinas or those over 21 years old may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating or preventing blindness by enhancing our understanding of retinal development.
How similar studies have performed: Other research has shown success in using molecular recording technologies to understand developmental processes, indicating that this approach has potential for significant findings.
Where this research is happening
PASADENA, UNITED STATES
- CALIFORNIA INSTITUTE OF TECHNOLOGY — PASADENA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TRAN, MARTIN — CALIFORNIA INSTITUTE OF TECHNOLOGY
- Study coordinator: TRAN, MARTIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.