Understanding how the rete ovarii affects female reproductive health and longevity
Official title: Functions of the rete ovarii in ovary development, adult homeostasis, and female reproductive longevity
Funded at University of Colorado Denver · NIH-11085941 · Data updated 2026-11-12
This study is looking at a part of the ovary called the rete ovarii to see how it affects women's reproductive health as they age, focusing on how it helps with the growth and quality of eggs, and it's for women who want to understand more about their reproductive health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | May 15, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $242,044 |
| NIH project number | 5R00HD103778-05 |
| Project ID | NIH-11085941 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adult females, particularly those interested in understanding reproductive health and aging.
✕Less likely to help
Patients who are prepubescent or those who have undergone surgical removal of the ovaries may not benefit from this research.
What this research studies
This research investigates the role of the rete ovarii, a structure in the ovary, in female reproductive aging and longevity. It aims to understand how this structure influences the number and quality of ovarian follicles, which are crucial for reproductive function. Using advanced 3D imaging techniques, the study will explore how the rete ovarii contributes to the assembly of ovarian cells and their development. By examining these factors, the research seeks to uncover new insights into female reproductive health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for enhancing female reproductive longevity.
How similar studies have gone: While the rete ovarii has been described anatomically, this research represents a novel approach to understanding its functional role in female reproductive health.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Mckey, Jennifer C — University of Colorado Denver
- Study coordinator: Mckey, Jennifer C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.