Understanding how the protozoan Trypanosoma cruzi feeds

Elucidating the Mechanistic Basis for Phagotrophy in the Protozoan Trypansoma cruzi

['FUNDING_R01'] · UNIVERSITY OF GEORGIA · NIH-11088289

This study looks at how the tiny organism Trypanosoma cruzi eats and digests food, which could help us learn more about the infections it causes and lead to better treatments for patients.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF GEORGIA (nih funded)
Locations1 site (ATHENS, UNITED STATES)
Trial IDNIH-11088289 on ClinicalTrials.gov

What this research studies

This research investigates the feeding mechanisms of the protozoan Trypanosoma cruzi, which is known for its role in various infections. The study focuses on the cytostome/cytopharynx complex, a structure that allows the organism to capture and digest nutrients. By examining how this feeding apparatus is formed and functions, the research aims to uncover fundamental biological processes that could have implications for understanding parasitic infections. Patients may benefit from insights gained about the biology of this parasite, which could inform treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals affected by Chagas disease, which is caused by Trypanosoma cruzi.

Not a fit: Patients with non-parasitic infections or unrelated health conditions may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for infections caused by Trypanosoma cruzi.

How similar studies have performed: While the specific mechanisms of feeding in Trypanosoma cruzi are not well-studied, similar research on other protozoan parasites has shown promising results in understanding their biology.

Where this research is happening

ATHENS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.