Understanding how the posterior cingulate cortex affects memory recall

Multimodal dissociation of posterior cingulate cortex contributions to episodic memory

NIH-funded research University of Pennsylvania · NIH-10892061

This study is looking at how a specific part of the brain helps us remember past experiences, and it's for people who want to understand more about their memory, especially those dealing with conditions like Alzheimer's disease.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10892061 on NIH RePORTER

What this research studies

This research investigates the role of the posterior cingulate cortex (PCC) in episodic memory, which is the ability to remember past experiences. By using advanced neuroimaging techniques, researchers will explore how different areas of the PCC are activated during various memory tasks, such as recognizing items versus recalling personal experiences. The study aims to clarify the unique contributions of the dorsal and ventral subregions of the PCC to memory processes. Patients may be involved in tasks that help researchers understand how their memory functions and how it may be affected by conditions like Alzheimer's disease.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals experiencing cognitive deficits or memory issues, particularly those diagnosed with Alzheimer's disease.

Not a fit: Patients with no memory issues or those not diagnosed with cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for memory-related conditions, particularly Alzheimer's disease.

How similar studies have performed: Previous research has shown promising results in understanding the role of the PCC in memory, indicating that this approach has a solid foundation in existing literature.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.