Understanding how the patient microbiome affects infections after spine surgery

Targeting the Patient Microbiome for the Prevention of Surgical Site Infection in Spine Surgery

NIH-funded research University of Washington · NIH-11010419

This study is looking at how the bacteria in your body might affect the risk of getting infections after spine surgery, and it aims to find ways to prevent these infections to help you heal better.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11010419 on NIH RePORTER

What this research studies

This research investigates the role of the patient microbiome in the development of surgical site infections (SSIs) following spine surgery. By analyzing the bacteria present in patients before and after surgery, the study aims to identify specific microbial strains that contribute to infections. The approach includes training in microbiome sciences and prospective data collection to better understand how these bacteria interact with surgical procedures. This knowledge could lead to improved prevention strategies for SSIs, ultimately enhancing patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients scheduled for instrumented spine surgery who are at risk for surgical site infections.

Not a fit: Patients who are not undergoing spine surgery or those with existing infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the rates of surgical site infections in patients undergoing spine surgery.

How similar studies have performed: Previous research has shown that understanding the microbiome can lead to successful interventions in infection prevention, suggesting a promising avenue for this study.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.