Understanding how the pancreatic tumor environment affects drug resistance
Integrating Spatial Omics and Drug Imaging to Dissect the Role of Pancreatic Tumor Microenvironment in Drug Resistance
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-10949009
This study is looking at how pancreatic tumors and their surroundings make it hard for cancer treatments to work, with the goal of finding better ways to help patients like you respond to therapy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10949009 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions within the pancreatic tumor microenvironment that contribute to drug resistance in cancer treatment. By integrating advanced imaging techniques and computational methods, the project aims to analyze how drugs interact with cancer cells and their surrounding environment at a single-cell level. Patients may benefit from this research as it seeks to uncover new strategies to enhance the effectiveness of cancer therapies, particularly for those with pancreatic cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with pancreatic cancer who are experiencing challenges with current treatment options.
Not a fit: Patients with cancers other than pancreatic cancer or those who are not currently undergoing treatment may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatments that overcome drug resistance, potentially increasing survival rates for patients with pancreatic cancer.
How similar studies have performed: Previous research has shown promise in using similar imaging and computational approaches to enhance cancer treatment outcomes, indicating a potential for success in this novel application.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LU, GUOLAN — STANFORD UNIVERSITY
- Study coordinator: LU, GUOLAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anti-Cancer Agents