Understanding how the nervous system affects airway diseases like asthma and COPD
Neurobiology of the Bronchopulmonary System
This study is looking at how the nerves in your airways might be causing breathing problems in conditions like asthma and COPD, especially after viral infections, to help find better treatments for people dealing with chronic cough and breathing issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11045788 on NIH RePORTER |
What this research studies
This research investigates the role of the nervous system in respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It focuses on how certain nerve fibers in the airways become overly active due to inflammation and how this affects breathing. By studying the mechanisms behind these changes, the research aims to uncover new insights into how respiratory diseases develop and persist, particularly after viral infections during critical developmental periods. The findings could lead to better treatments for patients suffering from chronic cough and airway hyperresponsiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with asthma or COPD, particularly those experiencing chronic cough or airway hyperresponsiveness.
Not a fit: Patients with respiratory conditions unrelated to nervous system involvement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for patients with asthma and COPD, potentially reducing symptoms and enhancing quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the nervous system's role in respiratory diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Undem, Bradley Joel — Johns Hopkins University
- Study coordinator: Undem, Bradley Joel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.