Understanding how the MYC protein influences cancer development
The MYC Transcription Factor Network and the Path to Cancer
This study is looking at how a protein called MYC can affect the growth of cancers, especially pancreatic cancer, and aims to find new ways to treat these diseases by understanding how MYC interacts with other proteins and changes how cells work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10930049 on NIH RePORTER |
What this research studies
This research investigates the role of the MYC transcription factor in cancer progression, particularly how its deregulation can lead to various types of cancers. The study focuses on the interactions between MYC and other proteins in a larger transcriptional network, aiming to uncover new therapeutic strategies for treating cancers like pancreatic adenocarcinoma. By examining how MYC alters gene expression and influences cellular metabolism, the research seeks to identify potential targets for cancer treatment. Patients may benefit from insights that could lead to innovative therapies tailored to their specific cancer types.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancers associated with MYC deregulation, such as pancreatic adenocarcinoma or B-cell lymphomas.
Not a fit: Patients with cancers not linked to MYC deregulation or those with non-cancerous conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients with MYC-driven cancers.
How similar studies have performed: Previous research has shown promising results in targeting MYC and its network in cancer treatment, indicating a potential for success in this approach.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Eisenman, Robert Neil — Fred Hutchinson Cancer Center
- Study coordinator: Eisenman, Robert Neil
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.