Understanding how the microbiome affects food allergies in young children

Systems approach to elucidate the microbiome's influence on the development of food allergies early in life

NIH-funded research Massachusetts General Hospital · NIH-10986081

This study is looking at how the tiny bacteria in kids' guts might affect their chances of developing food allergies, and it's for children under 11 years old to help us learn more about what causes these allergies early on.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10986081 on NIH RePORTER

What this research studies

This research investigates the relationship between the microbiome and the development of food allergies in children under 11 years old. By analyzing gut bacteria through advanced sequencing techniques, the study aims to uncover how these microorganisms influence immune responses related to food allergies. The research involves building a large cohort of young patients to collect and analyze data over time, providing insights into the early factors that may contribute to food allergies. The principal investigator, Dr. Victoria M. Martin, is focused on integrating systems biology with clinical research to better understand these complex interactions.

Who could benefit from this research

Good fit: Ideal candidates for participation are children under 11 years old who may be at risk for developing food allergies.

Not a fit: Patients who are older than 11 years or do not have any risk factors for food allergies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing or managing food allergies in children.

How similar studies have performed: Previous research has shown promising results in understanding the microbiome's role in various allergic conditions, suggesting potential for success in this area as well.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.