Understanding how the microbes in our bodies affect health and disease

Human Microbiome Compendium: large-scale curation and processing of human microbiome datasets

NIH-funded research University of Chicago · NIH-10891469

This study is looking at the tiny germs in our bodies to see how they affect our health and diseases, and it's for anyone interested in understanding how these microbes might help us find better ways to diagnose and treat illnesses.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10891469 on NIH RePORTER

What this research studies

This research focuses on the human microbiome, the vast community of microorganisms living in and on our bodies, and their role in health and disease. By creating a comprehensive database that aggregates and processes over 750,000 microbiome samples, researchers aim to uncover hidden patterns and relationships between these microbes and various health conditions. The project will utilize advanced automated methods to analyze complex datasets, making it easier for scientists to identify potential causes of diseases linked to the microbiome. This could lead to improved diagnostic tools and new therapeutic approaches based on microbiome health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with conditions that may be linked to microbiome imbalances, such as gastrointestinal disorders, autoimmune diseases, or metabolic syndromes.

Not a fit: Patients with conditions unrelated to the microbiome or those who do not have access to the necessary data collection methods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and innovative treatments for diseases influenced by the microbiome.

How similar studies have performed: Previous research has shown promising results in understanding the microbiome's impact on health, suggesting that this approach could yield significant insights.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.