NIH-funded research R01 grant

Understanding how the medial temporal lobe affects visual perception and memory.

Official title: Visual perception and the medial temporal lobes

Funded at University of California at Davis · NIH-10869131 · Data updated 2026-11-12

This study is looking at how changes in a part of the brain called the medial temporal lobe can affect how we see and remember things, especially for people with Alzheimer's Disease, to help us understand why some might struggle with tasks like driving.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis
NIH-funded
Lab location1 site (Davis, United States)
Project startJuly 1, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$605,903
NIH project number1R01EY035249-01A1
Project IDNIH-10869131 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with Alzheimer's Disease, as well as those with other conditions affecting the medial temporal lobe.

Less likely to help

Patients with visual perception issues not related to medial temporal lobe dysfunction may not benefit from this research.

What this research studies

This research investigates the role of the medial temporal lobe (MTL) in visual perception and working memory, particularly in individuals with conditions like Alzheimer's Disease. It aims to understand how damage or age-related changes in the MTL can disrupt our ability to perceive complex visual scenes, such as while driving. The study will utilize a combination of psychophysical methods, eye tracking, and brain imaging to explore these processes in both healthy individuals and patients with MTL lesions. By addressing these questions, the research seeks to enhance our understanding of visual cognition and its implications for various neurological conditions.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for patients with visual perception deficits related to Alzheimer's Disease and other conditions.

How similar studies have gone: Previous research has shown promising results in understanding the role of the medial temporal lobe in memory and perception, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of California at Davis
    Davis, United States
    Active

Researchers

  • Principal investigator: Yonelinas, Andrew P — University of California at Davis
  • Study coordinator: Yonelinas, Andrew P

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.