Understanding how the influenza D virus infects different animals and humans
Influenza D Virus Entry and Tissue Tropism
['FUNDING_R01'] · UNIVERSITY OF KENTUCKY · NIH-10472657
This study is looking at how the influenza D virus, which mainly affects cattle but can also infect humans and other animals, attaches to cells in our bodies, helping us understand how it spreads and what it might mean for our health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KENTUCKY (nih funded) |
| Locations | 1 site (LEXINGTON, UNITED STATES) |
| Trial ID | NIH-10472657 on ClinicalTrials.gov |
What this research studies
This research investigates the influenza D virus (IDV), which primarily infects cattle but can also spill over to other mammals, including humans. The study focuses on how IDV binds to specific receptors in human and animal cells, which may lead to infections. By examining the differences in how IDV and human influenza C virus interact with these receptors, researchers aim to uncover the mechanisms that allow IDV to infect various species. This could provide insights into the virus's behavior and its potential impact on public health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been exposed to livestock or have experienced symptoms related to influenza-like illnesses.
Not a fit: Patients who have no history of exposure to animals or who do not exhibit any symptoms related to influenza may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of influenza D virus infections in humans and animals.
How similar studies have performed: Previous research on similar viral mechanisms has shown promise in understanding viral infections, suggesting that this approach could yield valuable insights.
Where this research is happening
LEXINGTON, UNITED STATES
- UNIVERSITY OF KENTUCKY — LEXINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LI, FENG — UNIVERSITY OF KENTUCKY
- Study coordinator: LI, FENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease, Disorder, Disease Outbreaks