Understanding how the immune system responds to SARS-CoV-2
Mechanisms and Duration of Immunity to SARS-CoV-2 - Supplement Application for Sept 2024-Aug 2025
This study is looking at how our immune system responds to the COVID-19 virus and vaccines, especially in different groups of people like pregnant individuals and those with long Covid, to help us understand how immunity works and lasts over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11159129 on NIH RePORTER |
What this research studies
This research investigates the immune responses to the SARS-CoV-2 virus, focusing on how the body reacts to both infection and vaccination. It aims to understand the mechanisms of immunity, including the role of B cells and T cells, and how these responses may differ in various populations, including pregnant individuals and those experiencing long Covid. The research employs advanced techniques such as single-cell sequencing and structural studies of antibodies to gain insights into the evolution of immune memory over time. By analyzing immune responses in diverse groups, the study seeks to provide a comprehensive understanding of how immunity develops and persists.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been infected with SARS-CoV-2, those who have received COVID-19 vaccinations, pregnant individuals, and patients experiencing long Covid.
Not a fit: Patients who have not been infected with SARS-CoV-2 and have not received any COVID-19 vaccinations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and treatments for COVID-19 and its long-term effects.
How similar studies have performed: Other research has shown success in understanding immune responses to coronaviruses, making this approach both relevant and promising.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Boyd, Scott Dexter — Stanford University
- Study coordinator: Boyd, Scott Dexter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.