Understanding how the immune system responds to influenza vaccines
Towards a predictive understanding of influenza immunity through experimental data integration, iterative model development, and rigorous assessment of model quality
['FUNDING_U01'] · LA JOLLA INSTITUTE FOR IMMUNOLOGY · NIH-11017579
This study is working on creating computer models to help predict how effective flu vaccines are by looking at different immune responses, which could lead to better vaccine strategies for everyone.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LA JOLLA INSTITUTE FOR IMMUNOLOGY (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11017579 on ClinicalTrials.gov |
What this research studies
This research aims to develop computational models that can predict how well influenza vaccines work based on various immunological factors. By analyzing existing data and generating new experimental information, the researchers will assess the immune responses triggered by the vaccine, including the roles of B cells and T cells. The project will also involve an annual competition to test the accuracy of these models using real-world data. Patients may benefit from improved vaccine strategies that enhance immunity against influenza.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who receive influenza vaccinations and have varying immune responses.
Not a fit: Patients who do not receive influenza vaccinations or have conditions that prevent them from mounting an immune response may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective influenza vaccines that provide longer-lasting immunity.
How similar studies have performed: Other research has shown promise in using computational models to predict vaccine responses, indicating that this approach has potential for success.
Where this research is happening
LA JOLLA, UNITED STATES
- LA JOLLA INSTITUTE FOR IMMUNOLOGY — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PETERS, BJOERN — LA JOLLA INSTITUTE FOR IMMUNOLOGY
- Study coordinator: PETERS, BJOERN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.