Understanding how the immune system responds to alcohol-related liver diseases

C-Type Lectins and Immune Surveillance in ALD

NIH-funded research University of Connecticut Sch of Med/dnt · NIH-10896993

This study is looking at how alcohol affects the immune system and liver health, especially in people with alcoholic hepatitis, to find better ways to treat and manage these conditions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Sch of Med/dnt NIH-funded
Lab location1 site (Farmington, United States)
Project IDNIH-10896993 on NIH RePORTER

What this research studies

This research focuses on the role of the immune system in alcohol-related liver diseases (ALD), particularly alcoholic hepatitis. The project aims to utilize bioinformatics and advanced sequencing techniques to analyze gene expression and regulation in the immune system. By studying how alcohol consumption affects gut barrier function and immune responses, the research seeks to uncover the mechanisms behind the inflammation associated with ALD. Patients may benefit from insights that could lead to improved treatments and management strategies for alcohol-related liver conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with alcohol-related liver diseases, particularly those experiencing alcoholic hepatitis.

Not a fit: Patients with liver diseases not related to alcohol consumption may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for patients suffering from alcohol-related liver diseases.

How similar studies have performed: Previous research has shown promising results in understanding immune responses in liver diseases, indicating that this approach could yield valuable insights.

Where this research is happening

Farmington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.