Understanding how the immune system regulates iron in the body during health and disease
Immune regulation of tissue iron in health and disease
['FUNDING_OTHER'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-11101241
This study is looking at how a hormone called hepcidin, which helps manage iron in the body, affects people with chronic diseases like inflammatory bowel disease, infections, and cancer, to better understand how iron and inflammation work together and improve treatment options for these conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded) |
| Locations | 1 site (Newark, UNITED STATES) |
| Trial ID | NIH-11101241 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between anemia and inflammation in chronic diseases such as inflammatory bowel disease, infections, and cancer. It focuses on a hormone called hepcidin, which controls iron release in the body and is affected by inflammation. The study aims to explore how hepcidin influences disease outcomes and to identify the specific cells involved in this process. By using advanced techniques, the research seeks to clarify the role of iron in managing inflammatory diseases and improving treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from chronic diseases that cause anemia, such as inflammatory bowel disease, infections, or cancer.
Not a fit: Patients with anemia not related to inflammation or chronic diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatments for anemia associated with chronic inflammatory diseases, improving patient outcomes.
How similar studies have performed: Previous research has shown promising results in understanding the role of hepcidin in anemia and inflammation, indicating that this approach has potential for significant advancements.
Where this research is happening
Newark, UNITED STATES
- RUTGERS BIOMEDICAL AND HEALTH SCIENCES — Newark, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BESSMAN, NICHOLAS J. — RUTGERS BIOMEDICAL AND HEALTH SCIENCES
- Study coordinator: BESSMAN, NICHOLAS J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anemia due to Chronic Disorder, anemia of chronic disease