Understanding how the immune system regulates inflammation in the intestines
Neuro-immune regulation of intestinal inflammation
This study is looking at how certain immune cells help control inflammation in the intestines, which could lead to new treatments for people with ulcerative colitis and Crohn's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10901872 on NIH RePORTER |
What this research studies
This research investigates the role of immune cells in managing inflammation in the intestines, particularly focusing on conditions like ulcerative colitis and Crohn's disease that affect millions of Americans. The study aims to identify new therapeutic targets by examining how certain immune cells respond to signals from the nervous system and other factors that influence inflammation and tissue repair. By exploring the functions of innate lymphoid cells and their interactions with various cytokines, the research seeks to develop better treatment options for patients suffering from inflammatory bowel diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with ulcerative colitis or Crohn's disease who are seeking new treatment options.
Not a fit: Patients with other gastrointestinal disorders unrelated to inflammatory bowel diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for patients with inflammatory bowel diseases.
How similar studies have performed: Previous research has shown promise in understanding immune regulation of inflammation, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Artis, David — Weill Medical Coll of Cornell Univ
- Study coordinator: Artis, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.